

Vapocoolant Studies
This meta-analysis (11 randomized controlled trials with 1410 patients) suggests that vapocoolant spray significantly decreased pain during intravenous cannulation when compared with placebo spray or no treatment in both adults and children.
Zhu Y, et al. | Read full study
The median pain of venipuncture was 3 in the placebo group and 1 in the vapocoolant group, P < .001.
Mace, SE et al. Department of Emergency Medicine, Cleveland Clinic | Read full study
A prospective study of 30 breast cancer patients found that using a sterile vapocoolant spray (nüm) before lymphoscintigraphy significantly reduced injection pain without affecting imaging results. All procedures were successful, with low pain scores reported and universal patient support for future use.
Tewari S, et al. | Read full study
Documents
Resources


sterile
gentle application
fast acting
single patient use
no loud noises
topical anethestic
Application Guidelines













